In 1952, Hisao Domoto primarily trained as a nihonga artist accompanied his renowned painter uncle, Insho Domoto to Paris where he embarked on the study of oil painting. During those years in Paris, he became friends with influential artists in the modern movement with painters such as Imai Toshimitsu and Kumi Sugai. Domoto garnered much attention due to his Abstractionist flair using thick oil paint with swirling dynamic forms in composition and intuitive properties.
In 1956, he became involved in the Art Informel movement brought about influence by art critic Michel Tapié that led to the introduction of Gutai art. After 1962, Domoto left the Art Informel and began searching for new forms of expression. He developed his "Ensembles Binaires" series consisting of repetitive flying strokes of dripping patterns and in the "Solutions des continuités" series where materiality was reinforced. Domoto's style underwent further changes from the late 1960s to the late 2000s, where he continued to produce experimental paintings such as the "Between Unconscious and Conscious" series, which was composed of intersecting circles and ripples that ebbed and flowed with dreamlike colors, along with automatism that uses blurring and blotting techniques.